Buy VIP Peptide in Australia
Buy VIP in Australia from Macropus Peptides as a 10mg research vial. VIP, vasoactive intestinal peptide, is a 28 amino acid neuropeptide first isolated from small intestine, and it is the reference agonist for the VPAC1 and VPAC2 receptors in neuroscience, immunology and gut physiology research. The 10mg vial carries a fixed price and is ready to order. Each vial holds freeze-dried powder under a crimped seal, labelled with compound, strength, lot number and storage temperature, with a certificate of analysis for every lot. The sequence includes a methionine that oxidises readily, so VIP vials should stay sealed and frozen until needed. Add bacteriostatic water to the order and we post it from our Australian shelves to any Australian address. For in-vitro laboratory research by adults only, never for human or animal use.
| Compound | VIP |
|---|---|
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Recovery research |
| Storage | -20 °C, protect from light |
| Testing | HPLC purity 98% or higher and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
VIP 10mg vial
Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.
Buy VIP Peptide Australia: 10mg Vial
Macropus Peptides stocks VIP as a priced 10mg vial of lyophilised vasoactive intestinal peptide, held in Australia and ready for checkout at a fixed list price. Receptor pharmacology, isolated tissue and immune cell laboratories use it as the reference VPAC agonist, and the lot number on every label points to a matching certificate of analysis.
VIP Australia: what vasoactive intestinal peptide is
It is a neuropeptide of 28 amino acids with an amidated end. It was first isolated from pig small intestine and described in Science in 1970, named for its effect on blood vessels. The synthetic chain reads HSDAVFTDNYTRLRKQMAVKKYLNSILN with a C-terminal amide, for a molecular weight close to 3,326. It belongs to the secretin and glucagon family of peptides and is closely related in sequence to PACAP, pituitary adenylate cyclase-activating polypeptide; roughly two thirds of its residues match PACAP-27, the shorter form of that relative, which is why the pair share receptors. Nerves throughout the gut, lungs, brain and immune organs release it. Its synthetic form is known internationally as aviptadil, and in Australia it is supplied as a research compound.
VIP peptide: how it works in research
The peptide signals through two receptors on the cell surface, VPAC1 and VPAC2. Both are G protein-coupled receptors linked to adenylyl cyclase, so activating them raises cyclic AMP inside the cell. PACAP binds these two receptors about as well, while a third receptor of the family, PAC1, strongly prefers PACAP. That naming system was set out in Pharmacological Reviews in 1998. In water the chain is mostly flexible, and it folds into a helix over much of its length in lipid or membrane-like surroundings, the conformation used in binding models. Peptidases in plasma and tissue cut it quickly, so experiments add it fresh and some buffers include protease inhibitors. Laboratories use it to study smooth muscle relaxation in isolated airway, vascular and gut strips, chloride secretion by intestinal lining cells, circadian signalling in the brain and messenger release by immune cells, often pairing it with selective VPAC1 or VPAC2 antagonists to tell the receptors apart.
VIP research: what the published studies show
The 1970 Science paper recorded the isolation and the first bioassays on blood vessels. The 1998 Pharmacological Reviews paper fixed the receptor names used today. In 2002 a paper in Cell reported that the VPAC2 receptor is needed for normal circadian function in the mouse suprachiasmatic nuclei, the brain clock, and the peptide has been a standard tool in clock research since. In 2004 a second review in Pharmacological Reviews covered its role in immune signalling, describing how the peptide and its receptors act on innate and adaptive immune cells. Much of this work uses cell lines, isolated tissue and rodent models. All four are listed in our neuropeptide research studies library.
VIP 10mg vial specifications
| Specification | Detail |
|---|---|
| Compound | VIP |
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Recovery research |
| Storage | -20 °C, protect from light |
White neuropeptide powder rests under the crimped closure. Each label shows strength, lot and storage temperature, and the lot fetches the batch certificate. A methionine at position 17 oxidises in air and in solution, so the vial is best kept sealed and frozen until needed. Loose flakes on the stopper after transit are normal for a freeze-dried fill; tap them back down before the seal is pierced.
VIP price in Australia: the 10mg list price per milligram
| Strength | Price | Price per mg |
|---|---|---|
| VIP 10mg | $119.99 | $12.00 per mg |
Our table lists one set Australian dollar figure for the ten milligram fill; split it ten ways and you have the milligram cost. Tissue bath and cell assays run at nanomolar to low micromolar concentrations, so one vial supports many concentration response curves. Groups planning a long series can put several vials in one cart so they share a synthesis lot, keeping certificate data consistent from the first experiment to the last. Against the 5mg LL-37 vial, this neuropeptide gives twice the material in a single fill.
VIP 10mg: one fill for receptor and tissue work
Ten milligrams is the only size we fill. At about 3,326 grams per mole, the vial holds close to 3.0 micromoles of peptide. Two millilitres of water make a 5 mg per mL stock, roughly 1.5 millimolar, and a thousandfold dilution of that into assay buffer lands near 1.5 micromolar, which suits the highest well of a cyclic AMP concentration series stepped down by factors of ten toward nanomolar levels. Most laboratories keep the concentrated stock and dilute it on the day, because dilute neuropeptide solutions lose material to enzymes and container walls.
Best place to buy VIP Australia
- Sold online at macropuspeptides.com, priced at $119.99
- Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
- A certificate of analysis for every lot, matched to the lot number printed on the label
- Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
- Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
- Payment by PayID or bank transfer, with your order ID as the reference
How to get VIP: ordering online
- Select the 10mg neuropeptide vial
- Set the vial count your assay series needs
- Add bacteriostatic water to the cart
- Check out, confirming adult research use
- Match the label lot to its certificate
VIP calculator: diluting the 10mg neuropeptide with bac water
The calculator turns any diluent volume into stock strength for the 10mg fill, using ten divided by the millilitres added. Two millilitres return 5 mg per mL, four return 2.5, five millilitres return 2 and the full 10 mL returns 1 mg per mL, which is 1,000 micrograms in each millilitre. Drawn with a U-100 syringe, where one unit is a hundredth of a millilitre, each unit of that 1 mg per mL solution holds 10 micrograms. Bacteriostatic water ships with the order if added, and syringes and other consumables are under lab supplies and kits.
Is VIP available in Australia
Only as a research peptide. The vials we sell have no therapeutic goods registration and no TGA approval, so supplying them for people or animals is not allowed. The TGA can amend the Poisons Standard at any time, so confirm the current classification of this neuropeptide and related peptides for your lab before ordering. Orders are accepted from adults for laboratory work only.
VIP for sale Australia wide: neuropeptide delivery to labs
Each parcel is dispatched from Australian stock and reaches research groups nationwide, among them Melbourne, Brisbane, Adelaide, Perth and Darwin, with no international freight or customs step on the way. Immunology groups often add Thymosin Alpha-1 or LL-37, gut barrier studies sometimes pair it with KPV, and more compounds are listed in our recovery research range.
References
- Polypeptide with broad biological activity: isolation from small intestine. Science. 1970.
- International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacological Reviews. 1998.
- The significance of vasoactive intestinal peptide in immunomodulation. Pharmacological Reviews. 2004.
- The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nuclei. Cell. 2002.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.