Buy SNAP-8 Peptide in Australia
Buy SNAP-8 in Australia from Macropus Peptides in a sealed 10mg vial. Also known as acetyl octapeptide-3, it is a synthetic eight amino acid peptide that copies part of SNAP-25, one of the three proteins that form the SNARE complex behind vesicle fusion and neurotransmitter release. Laboratories use it in SNARE assembly assays, exocytosis models and formulation stability work. Each vial holds lyophilised research material labelled with compound, fill, lot number and storage temperature, and every lot has a certificate of analysis available on request. The 10mg vial carries a fixed list price, and one vial covers a series of assays on a single lot. Order SNAP-8 online with bacteriostatic water, add GHK-Cu for related matrix work, and your parcel is sent from inside Australia to any Australian address. Supplied to adults for in-vitro laboratory research only, not for application to people or animals.
| Compound | SNAP-8 |
|---|---|
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Longevity and cognitive |
| Storage | -20 °C, protect from light |
| Testing | HPLC purity 98% or higher and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
SNAP-8 10mg vial
Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.
Buy SNAP-8 Australia: 10mg Research Peptide Vial
Macropus Peptides lists this acetylated octapeptide in a single 10mg vial for cell biologists and formulation chemists who study SNARE-dependent vesicle fusion. It carries a fixed list price and can be ordered online now. A single vial supports a series of exocytosis assays or formulation stability runs on a single lot.
SNAP-8 Australia: what the peptide is
SNAP-8, also known by its ingredient name acetyl octapeptide-3, is a synthetic chain of eight amino acids: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2. The acetyl group at the start and the amide at the end remove the terminal charges, which makes the peptide less vulnerable to enzymes that trim from the ends. Its sequence reproduces part of the N-terminal region of SNAP-25, one of the proteins that drive vesicle fusion in nerve cells. It is an extended version of acetyl hexapeptide-3, with alanine and aspartic acid added at the carboxyl end; the shorter peptide stops at Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Native SNAP-25 is a 206 residue protein, so the octapeptide represents only a small fragment of its first helix. With three acidic residues against two arginines and both ends capped, it carries a net charge of about minus one at neutral pH, so plain bacteriostatic water takes it up without trouble.
SNAP-8 peptide: how the SNAP-25 mimic works in research
Nerve cells release their chemical messengers when vesicles fuse with the outer membrane, a step driven by the SNARE complex. Three proteins form it, syntaxin, SNAP-25 and synaptobrevin, twisting together into a bundle of four helices that pulls the two membranes into contact. Short peptides copying the N-terminal segment of SNAP-25 are proposed to compete with the native protein for its place in that bundle, so that fewer complete complexes assemble. The mechanism is competition without cleavage, unlike bacterial neurotoxins that cut SNAP-25 outright. Researchers use the octapeptide in SNARE assembly assays, in neurotransmitter release models such as chromaffin cells, and in head-to-head comparisons with the shorter hexapeptide.
SNAP-8 research: what the studies show
The biology behind it is well documented even though peer-reviewed work on the octapeptide itself is limited. SNAP receptor proteins were identified as the machinery of vesicle docking and fusion in a 1993 paper in Nature, and the structure of the synaptic SNARE core complex was solved by X-ray crystallography and published in Nature in 1998. A 2002 study in the International Journal of Cosmetic Science examined the parent hexapeptide, measuring SNARE complex formation and catecholamine release from chromaffin cells. Much of the characterisation specific to the eight-residue version comes from manufacturer data rather than independent papers. The studies are listed in our SNAP-8 research studies library.
SNAP-8 vial specifications
| Specification | Detail |
|---|---|
| Compound | SNAP-8 |
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Longevity and cognitive |
| Storage | -20 °C, protect from light |
Each crimped vial carries the octapeptide as lyophilised powder; the label names it and gives the 10mg fill, a lot code and a freezer temperature, and that code retrieves its certificate of analysis on request. The methionine at position three oxidises readily to methionine sulfoxide, a change that alters binding and shows up on mass spectrometry, so hold the octapeptide frozen near -20 °C, shielded from light, and limit air exposure once it is opened. Because the vial holds raw peptide for bench work rather than a formulated cosmetic ingredient, its certificate reports the identity and purity of the octapeptide alone, with no carrier, preservative or solvent in the powder.
SNAP-8 price in Australia: cost per milligram
| Strength | Price | Price per mg |
|---|---|---|
| SNAP-8 10mg | $49.99 | $5.00 per mg |
Each 10mg vial sells at one set figure in local currency, so a milligram of octapeptide costs a tenth of the vial. That makes it one of the lower-cost vials in our catalogue per milligram, which suits formulation laboratories that spike the octapeptide into many test matrices and need several vials from one lot for a stability programme.
SNAP-8 10mg: the single fill to order
Our single 10mg fill covers a run of SNARE assembly or release assays, or a set of formulation stability samples, all on one lot. In 2 mL of bacteriostatic water the octapeptide reaches 5 mg per mL, and 4 mL halves that to 2.5 mg per mL for spiking into test matrices. At 5 mg per mL, twenty 0.1 mL aliquots hold 0.5mg apiece, enough for a stability series sampled week by week. Mark each aliquot with its lot and preparation date so oxidation can be traced if results drift. At about 1,075 g/mol, 5 mg per mL corresponds to roughly 4.7 millimolar, and a thousandfold dilution to about 4.7 micromolar, useful anchors when a SNARE assembly protocol is written in molar units.
Where to buy SNAP-8 in Australia
- Sold online at macropuspeptides.com, priced at $49.99
- Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
- A certificate of analysis for every lot, matched to the lot number printed on the label
- Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
- Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
- Payment by PayID or bank transfer, with your order ID as the reference
How to get SNAP-8: ordering online
- Place the 10mg octapeptide vial in the cart
- Set the quantity your assay or stability run needs
- Include bacteriostatic water or plan to use your own solvent
- Pay after ticking the adult research declaration
- Record the lot number so the certificate can be matched
SNAP-8 calculator: stock strength from the 10mg vial with bac water
Take 10 and divide by the diluent volume in millilitres: the octapeptide reaches 10 mg per mL in 1 mL, 5 in 2 mL, 2.5 in 4 mL and 1 in 10 mL. Buy bacteriostatic water 10mL with the peptide or pick another diluent from our lab supplies.
Is SNAP-8 legal in Australia
Yes, as a raw research peptide. Raw octapeptide is not a finished consumer product, is absent from the ARTG, lacks TGA approval, and must never be applied to people or animals. Scheduling rests with the TGA; look up where the Poisons Standard places it for your work before you order.
SNAP-8 for sale Australia wide: laboratory delivery
From Hobart and Canberra to Cairns and Geraldton, cell biology and formulation laboratories are sent vials dispatched from Australian stock, with nothing held at an international border. Matrix researchers often add GHK-Cu, a copper-binding tripeptide, or KPV, a tripeptide from the end of alpha-MSH, and other compounds are grouped in our longevity and cognitive range.
References
- A synthetic hexapeptide (Argireline) with antiwrinkle activity. International Journal of Cosmetic Science. 2002.
- Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature. 1998.
- SNAP receptors implicated in vesicle targeting and fusion. Nature. 1993.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.