For laboratory research use only · Not for human or veterinary use · 18+
Longevity and cognitive

Buy Semax Peptide in Australia

Lyophilised powder, 5mg vial · Available to order, dispatched from Australia
Choose strength: 5 MG
$59.99

Buy Semax in Australia from Macropus Peptides in 5mg and 10mg freeze-dried vials. Semax is a synthetic heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro, that joins the ACTH 4 to 7 fragment to a Pro-Gly-Pro tail, giving a melanocortin-derived peptide without the adrenal activity of the full hormone. It is used in rodent and tissue research on neurotrophin gene expression, including BDNF and its receptor TrkB. Both strengths are priced for immediate checkout, and a ready-mixed nasal spray and a starter kit are listed as separate products. Every vial is sealed, labelled with compound, strength, lot and storage temperature, and backed by a certificate of analysis for its lot. Buy Semax online with bacteriostatic water in the same order and we send it from Australian stock to any address in the country. For in-vitro laboratory research only, sold to adults, not for human or veterinary use.

1
Frequently bought together
Selank 5mg$59.99
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
CompoundSemax
Amount5 mg
FormLyophilised powder
CategoryLongevity and cognitive
Storage-20 °C, protect from light
TestingHPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label
Peptide calculator

Semax 5mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Vial content
5 mg
mg per mL2.50
mcg per mL2,500

Buy Semax Australia: 5mg and 10mg Vials

We supply this heptapeptide to Australian research groups as lyophilised powder in a 5mg and a 10mg vial, both priced, in stock and ready for checkout. One synthesis route and one release process sit behind both, so a protocol written around one vial size transfers to the other by adjusting the volume of diluent. The same compound also appears as a ready-mixed nasal spray, in a starter kit and in a blend with its sister peptide.

Semax Australia: what the peptide is

This is a seven residue synthetic peptide, Met-Glu-His-Phe-Pro-Gly-Pro. The first four amino acids copy positions 4 to 7 of adrenocorticotropic hormone (ACTH), a short melanocortin fragment known to act in the nervous system without triggering steroid release from the adrenal gland. On their own those four residues are cleared quickly, so developers in Moscow added a Pro-Gly-Pro tail to the carboxyl end, which slows cleavage by peptidases. The compound is often written as an ACTH(4-10) analogue. It holds a registration in Russia but is unregistered in Australia and is sold here only as a research chemical.

Semax peptide: how the ACTH fragment works in research

The mechanism studied most is neurotrophin signalling. In rat experiments the peptide changes transcription of brain-derived neurotrophic factor (BDNF) and its receptor TrkB in the hippocampus and cortex, which makes it a tool for work on how neurotrophin genes are switched on. In models of reduced blood flow to the brain, genome-wide studies have followed its effect on clusters of immune and vascular genes. Because of its ACTH origin, it is also studied as a melanocortin fragment that lacks adrenal activity. The Pro-Gly-Pro tail is a biologically active glyproline in its own right, and some studies compare the whole heptapeptide with that tripeptide alone to separate the two contributions.

Semax research: what the studies show

The core English-language papers are rodent studies of gene expression. Brain Research carried a 2006 paper that tracked hippocampal BDNF and TrkB messenger RNA and protein in rats, measured together with a conditioned avoidance test. In 2010, Cellular and Molecular Neurobiology reported on transcription of neurotrophins and their receptors after cerebral ischaemia in rats, comparing the heptapeptide with Pro-Gly-Pro. A genome-wide transcriptional analysis in BMC Genomics in 2014 examined immune and vascular gene expression in rat brain focal ischaemia. A 2001 biochemistry paper also measured inhibition of enkephalin-degrading enzymes in human serum by this peptide and Selank. Browse every study in our Semax research studies library, with model and design noted.

Semax vial specifications

SpecificationDetail
CompoundSemax
Amount5 mg
FormLyophilised powder
CategoryLongevity and cognitive
Storage-20 °C, protect from light

Each vial holds a dry cake, molecular weight about 814 g/mol, closed with a rubber stopper and crimped cap. Printed on the label are the compound, fill in milligrams, lot code and freezer setting. The N-terminal methionine can oxidise in solution, which is one more reason the powder stays sealed and frozen until needed. The certificate of analysis is issued against the lot code. The peptide is freely soluble in water, so bacteriostatic water needs no added acid or base to clear the cake.

Semax price: 5mg and 10mg vials in Australian dollars

StrengthPricePrice per mg
Semax 5mg$59.99$12.00 per mg
Semax 10mg$99.99$10.00 per mg

A fixed price applies to each vial, and both can be checked out now. Doubling the fill from 5mg to 10mg adds roughly two thirds to the price, so the larger vial works out cheaper per milligram, while the smaller one keeps the outlay down for a pilot. Two other listings change the arithmetic: the Semax starter kit adds diluent, syringes and swabs to the same vial, and the nootropic kit pairs it with Selank in separate vials for comparison work.

Semax 10mg: the standard vial to order

Ten milligrams is the standard purchase, large enough to take a neurotrophin expression study from pilot through to replicate runs on a single lot. Made up with 2 mL, the stock reads 5 mg/mL; made up with 5 mL it is a more dilute 2 mg/mL that splits easily into small aliquots. At 2 mg/mL, fifty portions of 0.1 mL hold 200 micrograms each, a convenient unit for a long series of cell or tissue runs. The starter kit version ships the same vial alongside 3 mL of diluent, a strip of ten half-mL syringes and swabs.

Semax 5mg: the vial for first experiments

The smaller vial is for method development and one-off runs, where opening a larger vial would leave peptide sitting in solution. Reconstituted with one millilitre it sits at 5 mg/mL, identical to the bigger fill made up with 2 mL, and with 5 mL it gives 1 mg/mL, the strength of the ready-mixed spray. Because the methionine oxidises once wet, a smaller stock that is finished quickly suits short studies well.

Semax vial or nasal spray: what to buy

The lyophilised vial is the laboratory format: you choose the diluent, the concentration and when to mix, and the dry powder keeps far longer than any solution. We also list a ready-mixed nasal spray as its own product, holding 10mg in 10 mL, or 1 mg/mL. The vial reaches that same strength with 10 mL of diluent, or five times it with 2 mL. Groups that need to prepare their own stocks or store material for months generally order the vial.

Where to buy Semax in Australia

  • Sold online at macropuspeptides.com in 5mg and 10mg, priced from $59.99
  • Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
  • A certificate of analysis for every lot, matched to the lot number printed on the label
  • Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
  • Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
  • Payment by PayID or bank transfer, with your order ID as the reference

How to get Semax: ordering online

  • Choose a strength, 5mg or 10mg, or take the starter kit
  • Enter a quantity, then add to cart
  • Include diluent if the lab needs it
  • Confirm adult research use at checkout
  • File the lot code; its certificate is sent on request

Semax calculator: bac water for the 5mg and 10mg vials

Divide the peptide in the vial by the water you add. Worked examples:

  • 10mg with 1 mL: 10 mg/mL
  • 10mg with 2 mL: 5 mg/mL
  • 10mg with 4 mL: 2.5 mg/mL
  • 10mg with 10 mL: 1 mg/mL
  • 5mg with 1 mL: 5 mg/mL
  • 5mg with 5 mL: 1 mg/mL

Molar protocols convert easily: at about 814 g/mol, a 5 mg/mL stock is close to 6.1 millimolar, and a thousandfold dilution of it sits near 6.1 micromolar. The calculator does the same sum for any volume and also reports mcg per mL. Order bacteriostatic water 10mL together with the heptapeptide, or see our lab supplies for other items.

Is Semax available in Australia

It is available here for research purposes only. The ACTH fragment analogue is absent from the ARTG, holds no TGA approval, and so may not reach humans or animals; our sales are limited to in-vitro work. Research peptides can be affected by changes to the Poisons Standard, so check the latest edition with your compliance officer first.

Semax for sale Australia wide: neuropeptide parcels to every state

Dispatched from Australian stock, Semax parcels reach metro and regional labs from Darwin to Geraldton, and no overseas freight or customs step sits in between. Researchers comparing glyproline peptides usually add Selank, or buy both in one vial as the glyproline blend. More neuropeptides appear in our longevity and cognitive range.

References

  1. Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia. Cellular and Molecular Neurobiology. 2010.
  2. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. BMC Genomics. 2014.
  3. Semax and selank inhibit the enkephalin-degrading enzymes from human serum. Bioorganicheskaia Khimiia. 2001.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

Questions about Semax

Chat on WhatsApp
Semax 5mg$59.99