Buy Melanotan 1 Starter Kit in Australia
Buy the Melanotan 1 starter kit in Australia from Macropus Peptides. Each kit contains a 10mg vial of lyophilised Melanotan 1, a 3 mL vial of bacteriostatic water, ten 0.5 mL insulin syringes and twenty alcohol swabs. Also known as afamelanotide, the peptide is a 13 amino acid analogue of alpha-melanocyte stimulating hormone with two substitutions that make it far more stable and potent than the natural hormone at the melanocortin 1 receptor. It is used in melanocyte and pigment biology research. The kit costs less than the 10mg vial and a water vial bought on their own, so the syringes and swabs add nothing to the bill. Each vial is lot-numbered, with the certificate of analysis for its lot on request. Order online for dispatch from our Australian shelves to every Australian state, strictly for in-vitro research by buyers aged 18 and over, not for human or veterinary use.
| Kit | Melanotan 1 starter kit |
|---|---|
| Amount | starter kit |
| Form | Research kit |
| Contents | Melanotan 1 10mg vial, BAC water 3 mL, 10 × 0.5 mL insulin syringes and 20 alcohol swabs |
| Category | Kits, stacks and value packs |
| Storage | See label |
| Testing | HPLC purity 98% or higher and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
Buy Melanotan 1 Starter Kit Australia: 10mg Vial and Mixing Supplies
Pigment biology laboratories come to this kit for the linear melanocortin analogue rather than its cyclic cousin. One 10mg vial, a small bottle of diluent and a set of syringes and swabs arrive together, ready for a first stock. Macropus Peptides packs the carton in Australia from the same lot-numbered supply as the single vial.
What afamelanotide is, and what the kit contains
Alpha-MSH is a 13 residue hormone cut from the precursor POMC. It switches on the melanocortin 1 receptor on melanocytes, the signal that drives eumelanin production, but it breaks down within minutes. Swapping methionine 4 for norleucine and L-phenylalanine 7 for its D form gives the linear analogue in this kit that resists enzymes and binds the receptor far more tightly. Its international name is afamelanotide; here it comes as 10mg of freeze-dried peptide under a crimped cap.
How Melanotan 1 works in research
MC1R is a G protein-coupled receptor. When an agonist binds it, adenylyl cyclase raises cyclic AMP inside the melanocyte, which activates the transcription factor MITF and, through it, the enzymes of melanin synthesis led by tyrosinase. The balance shifts toward dark eumelanin rather than the red-yellow pheomelanin. Because the analogue keeps the full 13 residue length and is linear, it is relatively selective for MC1R compared with shorter cyclic melanocortin peptides that reach MC3R and MC4R in the brain. Researchers use it in cultured melanocytes and skin models to study that receptor pathway, DNA repair responses after ultraviolet exposure and how receptor variants change signalling. It also serves as a reference agonist when new MC1R ligands are screened, because its potency and stability are well characterised.
Afamelanotide in the research record
PNAS carried the first description of the modified sequence in 1980, reporting unusually long melanotropic activity in animal tissue. The melanocortin receptor family was cloned and reported in Science in 1992, giving the target a molecular identity. The journal Peptides reviewed its development in 2006, and NEJM carried a clinical study in erythropoietic protoporphyria in 2015. Each design appears in the melanocortin research library.
Afamelanotide kit: items and specifications to order
| Specification | Detail |
|---|---|
| Kit | Melanotan 1 starter kit |
| Amount | starter kit |
| Form | Research kit |
| Contents | Melanotan 1 10mg vial, BAC water 3 mL, 10 × 0.5 mL insulin syringes and 20 alcohol swabs |
| Category | Kits, stacks and value packs |
| Storage | See label |
The carton carries the lot-coded 10mg peptide vial, a 3 mL bacteriostatic water bottle, ten insulin syringes and twenty alcohol swabs, all sealed.
Afamelanotide price against the separate parts
| Option | Price |
|---|---|
| Melanotan 1 starter kit | $99.99 |
Order the 10mg vial and a 3 mL water vial as two lines and the pair already costs more than this kit. The syringes and swabs are therefore included at no charge, and a laboratory needing only more peptide later can reorder the single vial.
The Melanotan 1 10mg vial
Ten milligrams is the one fill we list for the linear analogue, enough for several millilitres of stock at the strengths most melanocyte assays call for. Linear melanocortin peptides are light-sensitive. Keep the powder in a -20 °C freezer, carton closed; after water goes in, it belongs in a dark fridge between 2 and 8 °C, with the vial wrapped or boxed so bench lighting does not reach it.
Diluent and consumables in the afamelanotide kit
Benzyl alcohol-preserved water keeps the melanocortin stock clean over repeated entries, each half-millilitre syringe gives a fine reading scale, and a swab wipes the septum before every draw. These items are kept at room temperature.
Best place to buy Melanotan 1 Australia
- Sold online at macropuspeptides.com, priced at $99.99
- Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
- A certificate of analysis for every lot, matched to the lot number printed on the label
- Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
- Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
- Payment by PayID or bank transfer, with your order ID as the reference
How to order the afamelanotide kit online
- Open the 10mg starter kit
- Choose the quantity
- Add a Melanotan II kit to compare
- Confirm adult research use at checkout
- Request the certificate for your lot
Afamelanotide 10mg: mixing the kit supplies
Dividing ten milligrams of the MC1R agonist by the water volume gives the answer. At 1.5 mL that is near 6.67 mg per mL; at 2 mL, exactly 5; the MC1R agonist in all 3 mL sits near 3.33. The kit syringes show fifty graduation ticks, a hundredth of a millilitre apart, across their 0.5 mL barrel, and at the 5 mg per mL strength each tick holds 50 micrograms. Swirl slowly and let any foam settle before drawing the first volume. Further diluent comes as bacteriostatic water 10mL.
Is Melanotan 1 legal in Australia
This lyophilised vial is not an ARTG-entered product, and we supply it purely for in-vitro research. A finished implant containing the same molecule is registered in some overseas jurisdictions for a rare light-sensitivity disorder, but that product and this research vial are unrelated. Melanocortin analogues have their own wording in the TGA's Poisons Standard, worth reading ahead of any purchase.
Afamelanotide for sale Australia wide
Kits ship from inside Australia to capitals and country towns alike. The stand-alone peptide is on the single 10mg vial listing. Related melanocortin bundles include the Melanotan II starter kit and the PT-141 starter kit, all within kits and stacks.
References
- 4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity. Proceedings of the National Academy of Sciences of the USA. 1980.
- The cloning of a family of genes that encode the melanocortin receptors. Science. 1992.
- Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006.
- Afamelanotide for erythropoietic protoporphyria. New England Journal of Medicine. 2015.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.