For laboratory research use only · Not for human or veterinary use · 18+
Melanocortin research

Buy Kisspeptin-10 Peptide in Australia

Lyophilised powder, 5mg vial · Available to order, dispatched from Australia
Choose strength: 5 MG
$74.99

Buy Kisspeptin-10 in Australia from Macropus Peptides in 5mg and 10mg lyophilised research vials. Kisspeptin-10 is the ten amino acid, amidated C-terminal fragment shared by all the kisspeptins, the natural ligands of the KISS1 receptor (formerly GPR54). It activates that receptor with full potency in a short, easily made sequence, and is used in neuroendocrine research on GnRH neurons and in cancer cell migration and invasion assays. Both vials are priced and ready to order: the 5mg fill suits a first receptor assay, and the 10mg fill gives the lower cost per milligram. Each vial is sealed and labelled with compound, strength, lot number and storage temperature, and a certificate of analysis is available for every lot. Add bacteriostatic water and the order ships from our Australian shelves to any address in the country. For in-vitro research by adults only, not for human or veterinary use.

1
Frequently bought together
PT-141 10mg$109.99
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
CompoundKisspeptin-10
Amount5 mg
FormLyophilised powder
CategoryMelanocortin research
Storage-20 °C, protect from light
TestingHPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label
Peptide calculator

Kisspeptin-10 5mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Vial content
5 mg
mg per mL2.50
mcg per mL2,500

Buy Kisspeptin-10 Australia: 5mg and 10mg Vials

Our decapeptide comes in a 5mg and a 10mg lyophilised fill, aimed at Australian neuroendocrine and cell biology laboratories, with a list price on each and stock on hand. A single synthesis feeds both fills and each lot is released with its own certificate; beyond the quantity of powder and the price per milligram, the two vials are identical.

Kisspeptin-10 Australia: what the peptide is

Kisspeptins are a family of peptides cut from one precursor protein encoded by the KISS1 gene. The longest circulating form has 54 amino acids, and every form ends in the same ten residues: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2. That shared tail is the decapeptide we sell, and it carries full activity at the receptor. The KISS1 gene was first described in 1996 in the Journal of the National Cancer Institute as a suppressor of metastasis in melanoma cells, before anyone knew what its peptide products bound to. The amidated Arg-Phe ending places the peptide in the RF-amide family. No regulator has approved it for any purpose, so it is sold purely for research.

Kisspeptin-10 peptide: how the KISS1R agonist works in research

In 2001 two groups, publishing in Nature and in the Journal of Biological Chemistry, showed that kisspeptins are the natural ligands of an orphan receptor then called GPR54, now KISS1R. The receptor couples to Gq/11 protein, activating phospholipase C and releasing calcium inside the cell. KISS1R is expressed on the neurons that release gonadotropin-releasing hormone (GnRH) in the hypothalamus, which is why the decapeptide became a central tool for studying how the brain controls the pituitary and gonads in animal models. The original cancer finding supports a second line of work: migration, invasion and receptor signalling assays in tumour cell lines. Typical readouts are intracellular calcium traces, inositol phosphate accumulation, ERK phosphorylation and electrophysiology on GnRH neurons in brain slices.

Kisspeptin research: what the published studies show

The record runs from gene discovery to receptor biology. The 1996 JNCI paper identified the KISS1 gene in melanoma cell lines. In 2001, Nature reported isolating the peptide from placenta and showing its binding to the receptor, and the Journal of Biological Chemistry described kisspeptins as GPR54 ligands with the receptor's tissue distribution. In 2003, PNAS reported loss-of-function mutations in the GPR54 gene in families with hypogonadotropic hypogonadism, which tied the receptor to the reproductive axis in humans. Each of these, with its model and design, is summarised in our Kisspeptin-10 research studies library.

Kisspeptin-10 vial specifications

SpecificationDetail
CompoundKisspeptin-10
Amount5 mg
FormLyophilised powder
CategoryMelanocortin research
Storage-20 °C, protect from light

The vial holds the decapeptide as a dry white powder, molecular weight about 1,302 g/mol, sealed under a stopper and aluminium crimp. The label gives compound, fill, lot number and a frozen storage temperature. The sequence contains a tryptophan that is sensitive to light and two asparagines that can deamidate in solution, so keep the powder frozen and dark and use mixed stock promptly. Certificates are released by lot number.

Kisspeptin-10 price in Australia: what each fill costs per mg

StrengthPricePrice per mg
Kisspeptin-10 5mg$74.99$15.00 per mg
Kisspeptin-10 10mg$99.99$10.00 per mg

Both fills are listed in Australian dollars. The 10mg vial holds twice the decapeptide of the 5mg vial for roughly a third more money, so it sets the lower cost per milligram. The 5mg vial costs less up front and wastes less when a project needs only a small stock, which matters for a sequence whose mixed solutions are best used quickly.

Kisspeptin-10 10mg: the better value per milligram

Pick the 10mg vial for a full concentration-response series or work across several cell lines on one lot. Reconstituted in 2 mL, the decapeptide gives 5 mg/mL; in 5 mL, 2 mg/mL. At about 1,302 g/mol, a 5 mg/mL stock is near 3.8 millimolar, and a millionfold dilution in two steps reaches about 3.8 nanomolar, so a single vial can feed many plates of a concentration series.

Kisspeptin-10 5mg: the smaller vial for first assays

Half the peptide of the 10mg fill, for a first receptor assay or for groups that prefer a fresh vial each run because mixed solutions of this sequence are best used quickly. Taken up in 2.5 mL, the smaller vial reaches 2 mg/mL, equal to its larger sibling in 5 mL, so one dilution scheme serves both. With 1 mL it gives a 5 mg/mL stock, matching the 10mg fill in 2 mL. Made up to 2 mL instead, at 2.5 mg/mL, it divides into ten portions of 0.2 mL holding 0.5mg apiece, a neat unit for a short series of calcium or migration assays that finishes before the solution ages.

Where to buy Kisspeptin-10 in Australia

  • Sold online at macropuspeptides.com in 5mg and 10mg, priced from $74.99
  • Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
  • A certificate of analysis for every lot, matched to the lot number printed on the label
  • Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
  • Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
  • Payment by PayID or bank transfer, with your order ID as the reference

How to get Kisspeptin-10: ordering online

  • Put the 5mg or 10mg fill in your cart
  • Choose your quantity, keeping one lot where possible
  • Add bacteriostatic water unless a diluent is on hand
  • Confirm adult research use at checkout
  • Match the lot on the label to its certificate

Kisspeptin-10 calculator: mixing the 5mg and 10mg fills

Fill in milligrams divided by water in millilitres gives the stock:

  • 10mg fill, 1 mL: 10 mg/mL
  • 10mg fill, 2 mL: 5 mg/mL
  • 10mg fill, 4 mL: 2.5 mg/mL
  • 5mg fill, 1 mL: 5 mg/mL
  • 5mg fill, 2 mL: 2.5 mg/mL

The calculator on the listing converts any volume to mg/mL and mcg/mL. Add bacteriostatic water 10mL from our lab supplies to the same parcel.

Is Kisspeptin-10 available in Australia

It is available for laboratory research and for no other purpose. The ARTG lists no kisspeptin product, no TGA approval exists, so the decapeptide may not go to humans or animals; in-vitro work is the only use we accept. Scheduling falls under the Poisons Standard, and your organisation should confirm the current position before ordering.

Kisspeptin-10 for sale Australia wide: laboratory delivery

Orders go out from Australian stock to laboratories in all capitals and regional centres, Launceston, Mildura and Mount Isa among them. Groups studying hypothalamic receptors often add PT-141 or Melanotan II, and growth hormone axis peptides live in our growth hormone research range. This decapeptide itself sits in the melanocortin research range.

References

  1. KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. Journal of the National Cancer Institute. 1996.
  2. Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature. 2001.
  3. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. Journal of Biological Chemistry. 2001.
  4. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proceedings of the National Academy of Sciences of the USA. 2003.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

Questions about Kisspeptin-10

Chat on WhatsApp
Kisspeptin-10 5mg$74.99