For laboratory research use only · Not for human or veterinary use · 18+
Kits, stacks and value packs

Buy 5-Amino-1MQ Starter Kit in Australia

5-Amino-1MQ 50mg vial, BAC water 3 mL, 10 × 0.5 mL insulin syringes and 20 alcohol swabs · Available to order, dispatched from Australia
$128.99

Buy the 5-Amino-1MQ starter kit in Australia and get the compound together with the supplies to put it into solution. Inside are one 50mg vial of 5-Amino-1MQ, a 3 mL vial of bacteriostatic water, ten 0.5 mL insulin syringes and twenty alcohol swabs. Unlike most lines in our catalogue, this is a small molecule rather than a peptide: a methylquinolinium compound designed to inhibit the enzyme nicotinamide N-methyltransferase, studied in cell and mouse models of metabolism. The kit costs less than the vial and a water vial bought on their own, before syringes and swabs are counted. Each vial is labelled with a lot number, and the certificate of analysis for that lot is supplied on request. Order the 5-Amino-1MQ kit online and it ships from Australia to any address in the country, to adult buyers for in-vitro laboratory research only, not for human or veterinary use.

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Frequently bought together
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
Kit5-Amino-1MQ starter kit
Amountstarter kit
FormResearch kit
Contents5-Amino-1MQ 50mg vial, BAC water 3 mL, 10 × 0.5 mL insulin syringes and 20 alcohol swabs
CategoryKits, stacks and value packs
StorageSee label
TestingHPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label

Buy 5-Amino-1MQ Starter Kit Australia: 50mg Vial with Supplies

Most research kits we pack centre on a peptide. This one centres on a small molecule, and its 50mg fill is ten times the mass of a typical 5mg peptide vial, which changes the concentration maths considerably. Alongside the inhibitor we pack a small bottle of preserved diluent, a set of half-millilitre syringes and a strip of swabs, while the vial itself is the same lot-coded material listed on its own.

What the 5-Amino-1MQ kit holds: a small molecule enzyme inhibitor

5-Amino-1-methylquinolinium is a compact, positively charged quinoline derivative, supplied here as a dry solid in a crimp-sealed vial. It was developed to block nicotinamide N-methyltransferase, known as NNMT, an enzyme expressed most strongly in liver and fat tissue. The permanent positive charge on its ring nitrogen is part of the design: it resembles the methylated product of the enzyme, one reason quinolinium compounds fit its active site. Details of the standalone product are on the 5-Amino-1MQ vial listing.

How 5-Amino-1MQ works in research

The enzyme's job is to hand a methyl group from S-adenosylmethionine, the principal methyl donor in cells, across to nicotinamide. That single reaction does two things at once. It consumes methyl donor, leaving S-adenosylhomocysteine behind, and it removes nicotinamide that would otherwise be recycled into NAD+ through the salvage pathway, excreting it instead as 1-methylnicotinamide. Blocking the enzyme is therefore expected to spare both pools. Laboratories use the inhibitor in cultured adipocytes, liver cells and mouse tissue to watch NAD+ levels, methylation capacity and lipid storage respond when that drain is closed, and to test how far NNMT activity explains differences between lean and enlarged fat cells.

5-Amino-1MQ research background

Interest in the target grew after a 2014 Nature paper found that reducing NNMT in adipose tissue of mice altered energy expenditure. A 2017 Journal of Medicinal Chemistry study mapped structure-activity relationships across quinolinium inhibitors, and Biochemical Pharmacology in 2018 reported selectivity, cell permeability and adiposity measures in mice on a high fat diet. A later paper in the same journal turned to muscle stem cells in aged mice. See the 5-Amino-1MQ research studies library for each design.

5-Amino-1MQ kit contents: specifications per order

SpecificationDetail
Kit5-Amino-1MQ starter kit
Amountstarter kit
FormResearch kit
Contents5-Amino-1MQ 50mg vial, BAC water 3 mL, 10 × 0.5 mL insulin syringes and 20 alcohol swabs
CategoryKits, stacks and value packs
StorageSee label
  • 50mg vial of 5-Amino-1MQ, sealed and lot-coded
  • 3 mL bacteriostatic water
  • Ten insulin syringes of 0.5 mL capacity
  • Twenty individually wrapped alcohol swabs

5-Amino-1MQ price and kit value

OptionPrice
5-Amino-1MQ starter kit$128.99

Priced one line at a time, compound and diluent alone exceed the kit total, before any syringe box or swab box is counted. If you only need extra compound later, the single vial remains available. The 50mg size is the single fill of the inhibitor that we stock.

The 5-Amino-1MQ 50mg vial

Ten times heavier than most peptide fills, the solid occupies a visible layer at the base of the glass rather than a thin film. It is a salt, so it dissolves readily in water without the coaxing some lipidated peptides need. Freezer storage at -20 °C, away from light, suits the dry quinolinium until use; the made-up solution is then chilled to 2 to 8 °C.

Diluent and consumables in the 5-Amino-1MQ kit

Three millilitres of preserved water is enough to make one stock at any of the common strengths and still leave a margin for rinsing or a second small preparation. The ten syringes each read to 0.01 mL across a half-millilitre barrel, and the twenty swabs cover a fresh wipe of the stopper for every withdrawal. Syringes, swabs and water are fine at room temperature.

Best place to buy 5-Amino-1MQ Australia

  • Sold online at macropuspeptides.com, priced at $128.99
  • Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
  • A certificate of analysis for every lot, matched to the lot number printed on the label
  • Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
  • Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
  • Payment by PayID or bank transfer, with your order ID as the reference

How to order the inhibitor kit online: 5 Amino 1MQ

  • Select the 50mg starter kit
  • Choose a quantity for your study
  • Add a 10mL water vial for weaker stocks
  • Confirm research use at checkout
  • Ask for the certificate for your lot

5-Amino-1MQ 50mg concentration maths with 3 mL

Dissolving the full fill in all 3 mL of water gives about 16.7 mg per mL. Cut the water to 2.5 mL and the compound sits at exactly 20 mg per mL; cut it to 2 mL and it reaches 25 mg per mL. Because the stock is strong, small volumes matter: each 0.5 mL syringe carries 50 marks of 0.01 mL, so readings are made in hundredths of a millilitre. At 20 mg per mL a single mark holds 200 micrograms. Where a weaker stock is preferred, a larger bacteriostatic water vial allows more dilution for a second, weaker preparation.

5-Amino-1MQ Australia: legal status

No quinolinium NNMT inhibitor appears on the ARTG; this one is sold for in-vitro chemistry and cell work only. The TGA maintains the Poisons Standard, which governs scheduling, so check it against your intended work.

Shop 5-Amino-1MQ and metabolic kits online, Australia wide

Our Australian dispatch reaches Darwin, Hobart and everywhere between, and the parcel never waits on customs. For NAD+ salvage work, the metabolic trio puts this inhibitor beside two other compounds, the MOTS-C starter kit covers the mitochondrial peptide alone, the NAD+ starter kit supplies the cofactor itself, and kits and stacks holds everything else.

References

  1. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014.
  2. Structure-activity relationship for small molecule inhibitors of nicotinamide N-methyltransferase. Journal of Medicinal Chemistry. 2017.
  3. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochemical Pharmacology. 2018.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

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5-Amino-1MQ starter kit$128.99