Buy Semax Peptide in Australia
Buy Semax in Australia from Macropus Peptides in 5mg and 10mg freeze-dried vials. Semax is a synthetic heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro, that joins the ACTH 4 to 7 fragment to a Pro-Gly-Pro tail, giving a melanocortin-derived peptide without the adrenal activity of the full hormone. It is used in rodent and tissue research on neurotrophin gene expression, including BDNF and its receptor TrkB. The 10mg vial is priced for immediate checkout and the 5mg vial is quoted on request. Every vial is sealed, labelled with compound, strength, lot and storage temperature, and backed by a certificate of analysis for its lot. Buy Semax online with bacteriostatic water in the same order and we send it from Australian stock to any address in the country. For in-vitro laboratory research only, sold to adults, not for human or veterinary use.
| Compound | Semax |
|---|---|
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Longevity and cognitive |
| Storage | -20 °C, protect from light |
| Testing | HPLC purity and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
Semax 10mg vial
Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.
Buy Semax Australia: 5mg and 10mg Vials
We supply this heptapeptide to Australian research groups as lyophilised powder in a 5mg and a 10mg vial. The larger strength is priced and in stock; the smaller one is quoted while its price is set. One synthesis route and one release process sit behind both, so a protocol written around one vial size transfers to the other by adjusting the volume of diluent.
What is the Semax peptide
Semax is a seven residue synthetic peptide, Met-Glu-His-Phe-Pro-Gly-Pro. The first four amino acids copy positions 4 to 7 of adrenocorticotropic hormone (ACTH), a short melanocortin fragment known to act in the nervous system without triggering steroid release from the adrenal gland. On their own those four residues are cleared quickly, so developers in Moscow added a Pro-Gly-Pro tail to the carboxyl end, which slows cleavage by peptidases. The compound is often written as an ACTH(4-10) analogue. It holds a registration in Russia but is unregistered in Australia and is sold here only as a research chemical.
How Semax works in research
The mechanism studied most is neurotrophin signalling. In rat experiments the peptide changes transcription of brain-derived neurotrophic factor (BDNF) and its receptor TrkB in the hippocampus and cortex, which makes it a tool for work on how neurotrophin genes are switched on. In models of reduced blood flow to the brain, genome-wide studies have followed its effect on clusters of immune and vascular genes. Because of its ACTH origin, it is also studied as a melanocortin fragment that lacks adrenal activity. The Pro-Gly-Pro tail is a biologically active glyproline in its own right, and some studies compare the whole heptapeptide with that tripeptide alone to separate the two contributions.
Semax research: what the studies show
The core English-language papers are rodent studies of gene expression. Brain Research carried a 2006 paper that tracked hippocampal BDNF and TrkB messenger RNA and protein in rats, measured together with a conditioned avoidance test. In 2010, Cellular and Molecular Neurobiology reported on transcription of neurotrophins and their receptors after cerebral ischaemia in rats, comparing the heptapeptide with Pro-Gly-Pro. A genome-wide transcriptional analysis in BMC Genomics in 2014 examined immune and vascular gene expression in rat brain focal ischaemia. A 2001 biochemistry paper also measured inhibition of enkephalin-degrading enzymes in human serum by this peptide and Selank. Browse every study in our Semax research studies library, with model and design noted.
Semax vial specifications
| Specification | Detail |
|---|---|
| Compound | Semax |
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Longevity and cognitive |
| Storage | -20 °C, protect from light |
Each Semax vial holds a dry cake, molecular weight about 814 g/mol, closed with a rubber stopper and crimped cap. Printed on the label are the compound, fill in milligrams, lot code and freezer setting. The N-terminal methionine can oxidise in solution, which is one more reason the powder stays sealed and frozen until needed. The certificate of analysis is issued against the lot code.
Semax price and cost in Australia
| Strength | Price | Price per mg |
|---|---|---|
| Semax 5mg | Price to confirm | - |
| Semax 10mg | $99.99 | $10.00 per mg |
A fixed price applies to Semax 10mg, and it can be checked out now. The 5mg vial is costed per enquiry. When that figure is published, expect the 10mg vial to remain cheaper per milligram, since one closure, label and set of lot documents covers twice as much peptide.
Semax 10mg: where to buy in Australia
Ten milligrams is the standard purchase, large enough to take a neurotrophin expression study from pilot through to replicate runs on a single lot. Made up with 2 mL, the Semax stock reads 5 mg/mL; made up with 5 mL it is a more dilute 2 mg/mL that splits easily into small aliquots.
Semax 5mg: quoted for first experiments
The smaller vial is for method development and one-off runs, where opening a larger vial would leave peptide sitting in solution. Reconstituted with one millilitre it sits at 5 mg/mL, identical to the bigger Semax fill made up with 2 mL. It is supplied on quote, so contact us before building a schedule around it.
Semax vial or nasal spray: what to buy
The lyophilised vial is the laboratory format: you choose the diluent, the concentration and when to mix, and the dry powder keeps far longer than any solution. We also list a ready-mixed Semax nasal spray as its own product at a fixed concentration. Groups that need to prepare their own stocks or store material for months generally order the vial.
Best place to buy Semax in Australia
- 5mg and 10mg vials, one synthesis
- Set pricing on 10mg, quotes on 5mg
- Lot code linked to a certificate
- Selank, its glyproline partner, in stock
- Dispatched from our Australian shelves, no customs delay
How to buy Semax online
- Choose Semax 10mg
- Or ask us to price 5mg
- Enter a quantity, then add to cart
- Include diluent if the lab needs it
- Confirm adult research use at checkout
Semax calculator: bac water for the 5mg and 10mg vials
Divide the peptide in the vial by the water you add. Worked Semax examples:
- 10mg with 1 mL: 10 mg/mL
- 10mg with 2 mL: 5 mg/mL
- 10mg with 4 mL: 2.5 mg/mL
- 5mg with 1 mL: 5 mg/mL
- 5mg with 5 mL: 1 mg/mL
The calculator does the same sum for any volume and also reports mcg per mL. Order bacteriostatic water 10mL together with the heptapeptide, or see our lab supplies for other items.
Is Semax available in Australia
It is available here for research purposes only. The ACTH fragment analogue is absent from the ARTG, holds no TGA approval, and so may not reach humans or animals; our sales are limited to in-vitro work. Research peptides can be affected by changes to the Poisons Standard, so check the latest edition with your compliance officer first.
Semax for sale Australia wide
Orders leave our Australian premises for capital cities and regional centres in every state and territory. Researchers comparing glyproline peptides usually add Selank, or buy both in one vial as the Semax and Selank blend. The Semax starter kit and more neuropeptides appear in our longevity and cognitive range.
References
- Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia. Cellular and Molecular Neurobiology. 2010.
- The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. BMC Genomics. 2014.
- Semax and selank inhibit the enkephalin-degrading enzymes from human serum. Bioorganicheskaia Khimiia. 2001.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.