Buy PT-141 Nasal Spray in Australia
Buy PT-141 nasal spray in Australia from Macropus Peptides: a 10mL bottle with 10mg of the melanocortin agonist already in solution, which is 1 mg per mL. PT-141, also known as bremelanotide, is a cyclic peptide closely related to Melanotan II that acts mainly at the MC3 and MC4 melanocortin receptors in the brain, and its early clinical pharmacology was carried out with an intranasal formulation. The solution is prepared before dispatch, so a laboratory has no powder to reconstitute and no diluent to buy. Every bottle is labelled with compound, amount, volume, concentration and lot number, with a certificate of analysis for each lot on request. The bottle is priced the same as our PT-141 10mg vial. Order PT-141 nasal spray online and it is dispatched cold from within Australia to any address in the country. Sold for in-vitro laboratory research only, to buyers aged 18 and over, and never for human or veterinary use.
| Compound | PT-141 nasal spray |
|---|---|
| Amount | 10 mg / 10 ml |
| Form | Nasal spray bottle, solution |
| Category | Melanocortin research |
| Storage | See label |
| Testing | HPLC purity and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
Buy PT-141 Nasal Spray Australia: 10mg per 10mL Bottle
Bremelanotide is available from Macropus Peptides both as a 10mg freeze-dried vial and as this pre-dissolved 10mL bottle. The liquid version carries the whole 10 milligrams, comes from the controlled supply behind our powder, and is batch-coded once filled. Melanocortin groups that would rather skip reconstitution order it for that reason.
PT-141 nasal spray Australia: what is in the bottle
Dissolving 10 mg to a 10 mL volume gives a strength of 1 mg per mL, which is 1,000 micrograms per millilitre. So 0.25 mL carries 250 micrograms and 3 mL carries 3 mg, which keeps laboratory maths simple. Under the metered pump top, the bottle is sealed, and its printed label identifies the peptide, the 10 mg content, the 10 mL fill, the strength and the batch.
How PT-141 works in research
The structure is Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It shares the lactam-bridged ring of Melanotan II and differs only at the end of the chain, where a free acid replaces an amide. That small change shifts its profile towards MC3R and MC4R, the two melanocortin receptors most strongly expressed in the central nervous system, where MC4R is a key node in hypothalamic signalling. Like other melanocortin agonists it acts through cyclic AMP. Laboratories use it for receptor binding and cyclic AMP assays, central melanocortin pathway work and structure-activity comparisons with its amide parent.
PT-141 research: the published record and the intranasal route
Binding work on it still rests on the 1992 Science paper that first cloned its target receptors. Endocrine Reviews surveyed what those receptors do physiologically in 2006, the same year Peptides charted how melanocortin analogues, bremelanotide among them, were developed. Its earliest clinical pharmacology studies, published from 2004, used an intranasal formulation, before a later phase 3 programme reported in 2019 switched to a different formulation. The route history is therefore documented, and the bottle mirrors the early format. Designs are summarised in our PT-141 research studies library.
PT-141 nasal spray specifications
| Specification | Detail |
|---|---|
| Compound | PT-141 nasal spray |
| Amount | 10 mg / 10 ml |
| Form | Nasal spray bottle, solution |
| Category | Melanocortin research |
| Storage | See label |
Labels list compound name, 10 mg total, 10 mL volume, 1 mg per mL and lot number. Of the two states, solution is the less stable for a peptide, so hold the bottle chilled, at 2 to 8 degrees and out of the light, and do not let it freeze. We provide the certificate belonging to whichever lot is printed on your bottle.
PT-141 nasal spray price in Australia
| Option | Price |
|---|---|
| PT-141 nasal spray 10mg / 10mL | $109.99 |
We charge the same Australian dollar amount for the bottle as for the 10mg vial, so the solution costs the same per milligram as the powder. The saving is in time and consumables, since no bacteriostatic water is needed.
Why buy PT-141 spray instead of the vial
A solution at a fixed 1 mg per mL gives every operator the same starting stock and removes a reconstitution step that can introduce error. It works well for MC4R and MC3R assays spread over several weeks, and for animal protocols tracing the compound's early intranasal history. The lyophilised vial is preferable for long frozen storage, for a buffer of your own choice, or for any concentration other than 1 mg per mL.
Best place to buy PT-141 nasal spray in Australia
- 10 mg in 10 mL, giving an exact 1 mg per mL
- Same price as the freeze-dried 10mg vial
- Every bottle lot-numbered with a certificate available
- Ready-made solution with no diluent required
- Cold-packed dispatch from local Australian stock
How to buy PT-141 nasal spray online
- Select the 10mL solution and place it in your cart
- Buy enough for the whole study so it stays on one lot
- Add the vial too if you need longer frozen storage
- Declare your age and research purpose when paying
- Refrigerate the bottle once delivered and request its certificate
PT-141 spray: caring for the solution after opening
Return the bottle to the refrigerator right after handling and keep the pump closure capped. Label it with the day it was opened and keep its lot number alongside every set of results. Replace any bottle that has frozen or been left at room temperature for an extended period.
Is PT-141 available in Australia
Only as a research peptide. Although the United States has approved bremelanotide as a medicine, Australia has not: it is missing from the ARTG and lacks TGA approval, so here it has no therapeutic sale and no use in humans or animals. Confirm your organisation's position under the Poisons Standard before ordering.
PT-141 nasal spray for sale Australia wide, chilled in transit
Bottles travel chilled from our Australian store to Perth, Melbourne, Brisbane, Adelaide, Darwin, Hobart and regional addresses. For comparison with its amide parent, add Melanotan II nasal spray, and for adjacent neuroendocrine work see Kisspeptin-10 in our melanocortin research range.
References
- The cloning of a family of genes that encode the melanocortin receptors. Science. 1992.
- Studies on the physiological functions of the melanocortin system. Endocrine Reviews. 2006.
- Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.