For laboratory research use only · Not for human or veterinary use · 18+
Melanocortin research

Buy PT-141 Peptide in Australia

Lyophilised powder, 10mg vial · Available to order, dispatched from Australia
$109.99

Buy PT-141 in Australia from Macropus Peptides as a 10mg lyophilised research vial. PT-141, known by the name bremelanotide, is a cyclic seven residue melanocortin peptide that differs from Melanotan II only at its end, a free acid in place of an amide. That change shifts its activity towards the MC4 and MC3 receptors, which are concentrated in the brain, and it is used in receptor binding, cyclic AMP and central melanocortin pathway research. The vial has a fixed price and is ready to order. It is sealed and labelled with compound, strength, lot number and storage temperature, with a certificate of analysis for each lot. Order online with bacteriostatic water and we send it from our Australian shelves to any Australian address. A nasal spray is listed separately. For in-vitro research by adults only, not for human or veterinary use.

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For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
CompoundPT-141
Amount10 mg
FormLyophilised powder
CategoryMelanocortin research
Storage-20 °C, protect from light
TestingHPLC purity and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label
Peptide calculator

PT-141 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Vial content
10 mg
mg per mL5.00
mcg per mL5,000

Buy PT-141 Australia: 10mg Vial

Macropus Peptides supplies this melanocortin agonist as a single 10mg freeze-dried vial with a set price, for laboratories in Australia studying central melanocortin receptors. The powder form keeps best in the freezer, and one strength keeps ordering and record keeping simple.

What is PT-141

PT-141 is the development code for bremelanotide, a synthetic cyclic heptapeptide, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It has exactly the ring and amino acids of Melanotan II, but ends in a free carboxylic acid where its parent carries an amide. It emerged from the same line of alpha-MSH analogue research as a deliberate variant of that parent. Bremelanotide was later approved as a medicine in the United States in 2019. It has no registration in Australia, where our vials are supplied only as research material.

How PT-141 works in research

Like other melanocortin agonists, the peptide activates receptors that couple to Gs protein and raise cyclic AMP. Its profile differs from its parent: activity is concentrated at MC4R and MC3R, the two melanocortin receptors most abundant in the brain, with weaker action at the others. MC4R sits at the centre of hypothalamic melanocortin signalling, a system reviewed in Endocrine Reviews in 2006 for its roles in energy balance and other functions. Researchers use this free-acid analogue to study MC4R and MC3R binding and activation, to compare it directly with the amide parent, and to probe central melanocortin pathways in rodent models.

PT-141 research: what the studies show

Its target receptors were among those first cloned in the family described by Science in 1992. The cyclic lactam scaffold it inherits dates from a 1989 Journal of Medicinal Chemistry paper. A 2006 review in Peptides explains how the free-acid form was selected from that series and taken into clinical study, and the same year Endocrine Reviews summarised what was known of melanocortin receptor physiology. Human trials were later published for its approved indication in the United States. Designs and models for every entry are set out in the PT-141 research studies library.

PT-141 vial specifications

SpecificationDetail
CompoundPT-141
Amount10 mg
FormLyophilised powder
CategoryMelanocortin research
Storage-20 °C, protect from light

Bremelanotide sits in the vial as a white lyophilised solid of roughly 1,025 g/mol, closed with a stopper and crimp. Its label shows compound, 10mg fill, lot and freezer storage. Protect it from light as well as heat, because the tryptophan in the ring is prone to photo-oxidation. The matching certificate of analysis is released against the lot.

PT-141 price in Australia

StrengthPricePrice per mg
PT-141 10mg$109.99$11.00 per mg

With one strength there is one Australian dollar price, and a milligram costs a tenth of it. When a study compares this peptide with its amide parent, ordering both in one checkout means both arrive and can be reconstituted together.

PT-141 10mg: where to buy in Australia

The 10mg vial is enough for a series of MC4R and MC3R binding or signalling experiments on one lot. Reconstituted in 2 mL, bremelanotide sits at 5 mg/mL; in 4 mL, 2.5 mg/mL. Smaller working solutions are then prepared from that stock.

PT-141 vial or nasal spray: the right format to buy

We list the peptide in two formats. The lyophilised vial is for laboratories that prepare their own stock solutions and want dry powder for long frozen storage. The PT-141 nasal spray is a separate product supplied in solution at a fixed concentration, and the PT-141 starter kit packs the vial with water and consumables.

Best place to buy PT-141 in Australia

  • Fixed-price 10mg vial
  • Certificate matched to each lot
  • Melanotan II stocked for side-by-side work
  • Sealed dry powder for storage
  • Australian stock, no customs wait

How to buy PT-141 online

  • Add the 10mg vial and quantity
  • Add Melanotan II for comparisons
  • Include water for mixing
  • Confirm adult research use
  • Record the lot on arrival

PT-141 calculator: how much bac water for the 10mg vial

Ten milligrams divided by the chosen volume gives the stock:

  • 1 mL: 10 mg/mL
  • 2 mL: 5 mg/mL
  • 2.5 mL: 4 mg/mL
  • 5 mL: 2 mg/mL

The PT-141 calculator converts other volumes into mg/mL and mcg/mL. Order bacteriostatic water 10mL alongside the vial; other consumables sit in lab supplies.

Is PT-141 available in Australia

As a research chemical, yes. No bremelanotide product holds an ARTG entry, so it may not be supplied here for human or veterinary use, and our vials are sold for in-vitro study only. Unregistered peptide scheduling comes from the TGA's Poisons Standard, which is updated regularly, so check its current terms before ordering.

PT-141 for sale Australia wide

Orders are dispatched from inside Australia to research addresses in all states and territories, metropolitan and regional. Melanotan II, Melanotan 1 and Kisspeptin-10 are listed in the same melanocortin research range.

References

  1. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006.
  2. Studies on the physiological functions of the melanocortin system. Endocrine Reviews. 2006.
  3. The cloning of a family of genes that encode the melanocortin receptors. Science. 1992.
  4. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics. Journal of Medicinal Chemistry. 1989.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

Questions about PT-141 10mg

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PT-141 10mg$109.99