Buy MOTS-C Peptide in Australia

Choose strength: 10 MG

10mg$99.9940mg$159.99

Buy MOTS-C in Australia from Macropus Peptides in two priced vial sizes, 10mg and 40mg. MOTS-C is a 16 amino acid peptide encoded in the mitochondrial genome rather than the nucleus, one of a small family of mitochondrial-derived peptides. It acts on the folate cycle and the energy sensor AMPK, and under metabolic stress it moves into the nucleus to influence gene expression, which makes it a key tool for studying how mitochondria signal to the rest of the cell. Each vial holds research-grade lyophilised powder, labelled with compound, strength, lot number and storage temperature, with a certificate of analysis for every lot. The 40mg vial costs less than half as much per milligram as the 10mg vial. Order MOTS-C online, add bacteriostatic water, and the parcel is sent from within Australia nationwide. For in-vitro laboratory research only, to buyers aged 18 and over; not for human or veterinary use.

Compound	MOTS-C
Amount	10 mg
Form	Lyophilised powder
Category	Metabolic research
Storage	-20 °C, protect from light
Testing	HPLC purity and mass spectrometry identity, every batch
Certificate of analysis	Available for every lot, matched to the lot number on the label

MOTS-C 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Diluent added (mL)

Buy MOTS-C Australia: 10mg and 40mg Vials

Macropus Peptides stocks this mitochondrial-derived peptide in 10mg and 40mg sizes, each with a listed price and ready to ship. Both are lyophilised from the same managed supply and released by lot, so stepping up a size only changes how much peptide you hold.

MOTS-C Australia: what is MOTS-C

The name stands for mitochondrial open reading frame of the 12S rRNA type-c. It is a 16-residue peptide, MRWQEMGYIFYPRKLR, encoded by a small open reading frame nested within the gene for 12S ribosomal RNA in mitochondrial DNA. That origin is unusual: almost every protein in the cell is encoded in the nucleus, but this one comes from the small mitochondrial genome. It belongs to the mitochondrial-derived peptide family alongside humanin, and our material is the synthetic peptide with the native human sequence.

MOTS-C peptide: mitochondrial signalling in research

In the discovery work, the peptide inhibited the folate cycle and the linked de novo purine synthesis pathway in cultured cells. That caused the intermediate AICAR to accumulate, and AICAR activates AMPK, the cell's main energy sensor, which in turn adjusts glucose uptake and fatty acid handling. Later work found that under metabolic stress, such as glucose restriction or oxidative stress, the peptide moves from the cytoplasm into the nucleus and binds chromatin, where it influences antioxidant response genes regulated by NRF2. A mitochondrial product that signals directly to nuclear gene expression is rare, and this retrograde role is the main reason laboratories study it.

MOTS-C research: what the published studies show

The peptide was first described in Cell Metabolism in 2015, in cell culture and mouse studies that examined AMPK signalling, glucose handling and insulin sensitivity. Its nuclear translocation was reported in Cell Metabolism in 2018, in cell stress experiments. A 2021 paper in Nature Communications measured how circulating and muscle levels change with exercise and examined skeletal muscle homeostasis in ageing mice. These three papers underpin most assay designs, and all are listed with design and measurements in our MOTS-C research studies library.

MOTS-C vial specifications

A white freeze-dried cake sits in the base of each crimp-sealed vial. Peptide name, strength, lot and freezer temperature appear on the label, and that lot pulls up the certificate for your batch. Sealed vials stay at -20 °C in darkness until needed.

MOTS-C price and MOTS-C cost in Australia

Both sizes carry listed prices. The 40mg vial holds four times the peptide of the 10mg vial but costs well under twice as much, which puts its cost per milligram at less than half that of the smaller size. The 10mg vial is the lower outlay for a first order.

MOTS-C 10mg: where to buy in Australia

The 10mg vial suits pilot studies, AMPK assay setup and groups using the peptide for the first time. It confirms a readout on one lot with a modest commitment. Three of these vials also come as the MOTS-C value pack. Stock strengths:

• 1 mL: 10 mg per mL
• 2 mL: 5 mg per mL

MOTS-C 40mg: the lowest price per milligram

Once a method is settled, the 40mg vial is where unit cost falls furthest. It holds four small vials' worth of peptide on a single lot, which helps time-course work where a batch change midway would add noise. Split the solution into single-use aliquots on the day it is mixed. Stock strengths:

• 4 mL: 10 mg per mL
• 8 mL: 5 mg per mL

Best place to buy MOTS-C Australia

• Two priced sizes, 10mg and 40mg, from one supply
• The 40mg vial at under half the per-milligram cost
• Lot code on the label, matched to a batch certificate
• Sent from local Australian stock within Australia, no customs queue
• Starter kit, value pack and metabolic trio options alongside

MOTS-C how to get: buy MOTS-C online

• Choose the 10mg or 40mg vial
• Pick a quantity and move to the cart
• Include a diluent vial when needed
• Pay, stating you are an adult researcher
• Keep the lot code for the certificate request

MOTS-C calculator: bac water for 10mg and 40mg vials

The listing's calculator turns any volume of diluent you enter into a MOTS-C concentration, in milligram and microgram units, for your size. The sequence begins with methionine and contains tryptophan, both prone to oxidation in solution, so keep mixed peptide cold and use it promptly. Order bacteriostatic water 10mL alongside, or choose the MOTS-C starter kit, which combines one 10mg vial, a 3 mL water vial, syringes and swabs.

Is MOTS-C available in Australia

Yes, as a research peptide. The ARTG holds no entry for this mitochondrial peptide and no TGA decision has approved it, so it is barred from supply for people or animals; we sell it for in-vitro laboratory work only. Its scheduling follows the Poisons Standard, which the TGA updates, so confirm the effect on your organisation before you order.

MOTS-C for sale Australia wide

Parcels ship from Australian stock to capital cities and regional research sites, with vials upright and caps protected. Mitochondrial research groups often add SS-31, which targets cardiolipin in the inner membrane, and NAD+ for cofactor work; the peptide also features in the metabolic trio. Browse the metabolic research range.

Questions about MOTS-C