Buy the MOTS-C, 5-Amino-1MQ and SLU-PP-332 Metabolic Trio in Australia
Buy the metabolic trio in Australia from Macropus Peptides: three separate research vials of MOTS-C, 5-Amino-1MQ and SLU-PP-332 under one price. Each compound reaches cellular energy metabolism from a different direction. MOTS-C is a mitochondria-encoded peptide linked to AMPK signalling, 5-Amino-1MQ is a small molecule that blocks the enzyme NNMT, and SLU-PP-332 is a synthetic activator of the oestrogen-related receptors that switch on oxidative genes. The trio costs less than buying the three priced single vials one at a time, and because nothing is premixed, each compound can be dissolved in its own solvent, run alone as a control or combined. Every vial is sealed, lot-numbered and labelled with strength and storage temperature, with a certificate of analysis on request. Add bacteriostatic water to the order and it ships from local Australian stock nationwide. For in-vitro laboratory research only, by purchasers aged 18 and over.
| Kit | Metabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332 |
|---|---|
| Amount | stack |
| Form | Research kit |
| Contents | MOTS-C, 5-Amino-1MQ and SLU-PP-332 in separate vials |
| Category | Kits, stacks and value packs |
| Storage | See label |
| Testing | HPLC purity and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
Buy the Metabolic Trio in Australia
Our metabolic trio combines three compounds that metabolic laboratories increasingly study together: MOTS-C, 5-Amino-1MQ and SLU-PP-332. They arrive as three sealed vials in one carton. Only one of the three is a peptide; the other two are small molecules, which is exactly why they are kept in separate vials rather than blended.
What is in the metabolic research trio
- One MOTS-C vial, lyophilised peptide
- One 5-Amino-1MQ vial, small molecule powder
- One SLU-PP-332 vial, small molecule powder
- Three labels, each carrying name, content, batch code and freezer temperature
MOTS-C is a sixteen residue peptide whose code sits inside the mitochondrial genome, in the 12S rRNA gene, rather than in the nucleus. Cell Metabolism carried the first report of it in 2015. Its single listing is MOTS-C.
5-Amino-1MQ is a methylquinolinium compound designed to block nicotinamide N-methyltransferase, an enzyme that uses up nicotinamide and methyl groups in fat and liver cells. See the 5-Amino-1MQ vial.
SLU-PP-332 is a synthetic agonist of all three oestrogen-related receptors, alpha, beta and gamma, nuclear receptors that drive mitochondrial and oxidative gene programmes. It is sold singly as SLU-PP-332 5mg.
Why the metabolic trio targets three pathways
The three act at separate control points. MOTS-C signals through AMPK and, under metabolic stress, moves into the nucleus, reported in Cell Metabolism in 2018. 5-Amino-1MQ works upstream on NAD+ and methyl-group balance: a 2014 Nature paper showed that knocking down NNMT changed energy expenditure in mice, and a 2018 Biochemical Pharmacology study tested small molecule NNMT inhibitors in high-fat diet mice. SLU-PP-332 acts at the level of gene transcription, examined in ACS Chemical Biology in 2023 and followed up by the same field in pharmacology journals during 2024. Having all three lets a study compare a signalling peptide, an enzyme inhibitor and a receptor agonist in one model. Records are in the MOTS-C research studies library.
Metabolic trio specifications
| Specification | Detail |
|---|---|
| Kit | Metabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332 |
| Amount | stack |
| Form | Research kit |
| Contents | MOTS-C, 5-Amino-1MQ and SLU-PP-332 in separate vials |
| Category | Kits, stacks and value packs |
| Storage | See label |
Three lots, three certificates: request each by the code on its vial. All three powders go straight into minus 20 °C storage on arrival, inside their carton or another dark container.
Metabolic trio price in Australia
| Option | Price |
|---|---|
| Metabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332 | $300.99 |
The trio's single price is lower than the combined list price of MOTS-C 10mg, 5-Amino-1MQ 50mg and SLU-PP-332 5mg bought as singles. No blend of these compounds exists, because their solvents and stabilities differ too much to share a vial.
Metabolic stack Australia: reconstitution and solvents
MOTS-C and 5-Amino-1MQ are normally made up in bacteriostatic water. Ten milligrams of MOTS-C taken up in two millilitres is a 5 mg per mL stock. For 5-Amino-1MQ, 50mg with 5 mL of water yields a 10 mg per mL stock. SLU-PP-332 is hydrophobic, so check its certificate and datasheet for the recommended solvent before adding water.
Metabolic trio Australia: legal status and dispatch
None of the three compounds holds ARTG registration, so the trio is sold only for in-vitro research. The TGA controls scheduling under the Poisons Standard; confirm your position before ordering. Orders ship from Australian stock to every state. The singles and related compounds such as Retatrutide sit in the metabolic research range.
References
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism. 2015.
- The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress. Cell Metabolism. 2018.
- Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014.
- Synthetic ERRalpha/beta/gamma agonist induces an ERRalpha-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chemical Biology. 2023.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.