Buy Melanotan II Peptide in Australia

Buy Melanotan II in Australia from Macropus Peptides as a 10mg freeze-dried research vial. Melanotan II is a seven residue cyclic analogue of alpha-MSH, closed by a lactam bridge, that acts as a non-selective agonist at the MC1, MC3, MC4 and MC5 melanocortin receptors. That broad profile makes it a standard pan-agonist control in receptor panels and structure-activity work, and it is the parent scaffold of PT-141. The vial is priced and can be ordered now. It is sealed, labelled with compound, strength, lot number and storage temperature, and a certificate of analysis is available for every lot. Order online, add bacteriostatic water for reconstitution, and your parcel ships from Australian stock to any address in the country. A ready-mixed nasal spray is listed separately. Sold to adults for in-vitro laboratory research only, not for human or veterinary use.

Compound	Melanotan II
Amount	10 mg
Form	Lyophilised powder
Category	Melanocortin research
Storage	-20 °C, protect from light
Testing	HPLC purity and mass spectrometry identity, every batch
Certificate of analysis	Available for every lot, matched to the lot number on the label

Melanotan II 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Diluent added (mL)

Buy Melanotan II Australia: 10mg Vial

We supply this cyclic melanocortin peptide in one priced strength, a 10mg lyophilised vial, for Australian receptor pharmacology and cell signalling laboratories. It ships as dry powder, the form in which it keeps longest, and every vial in an order is drawn from the same released lot wherever stock allows.

What is Melanotan II

This is a small synthetic analogue of alpha-MSH, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2. A lactam bond between the side chains of aspartic acid and lysine closes a ring around His-D-Phe-Arg-Trp, the four residue core that every natural melanocortin uses to activate its receptors. Locking that core into a ring makes the molecule far more stable against enzymes than the linear hormone. The cyclic series first appeared in a 1989 medicinal chemistry paper as a compact successor to the linear analogue Melanotan 1. It has never gained approval as a medicine anywhere and reaches laboratories purely as a research compound.

How Melanotan II works in research

Of the five melanocortin receptors, MC2R responds only to ACTH. The cyclic peptide activates the other four without clear preference, each coupling to Gs protein to raise cyclic AMP. That broad profile is the reason laboratories buy it: it serves as the pan-agonist control against which subtype-selective ligands are measured. It is also the scaffold behind several important tools. Changing its D-phenylalanine to a bulkier residue produced a well-known MC3R and MC4R antagonist, and removing the C-terminal amide produced PT-141. Typical uses are binding panels across receptor subtypes, cyclic AMP assays in transfected cell lines and studies of central melanocortin pathways in rodents.

Melanotan II research: what the studies show

The founding paper (Journal of Medicinal Chemistry, 1989) set out the design of cyclic lactam analogues and measured their potency and duration in bioassays. Cloning of the melanocortin receptor genes, published by Science in 1992, supplied the targets it was later profiled against. A pilot phase 1 study in Life Sciences in 1996 recorded skin pigmentation and tolerability in a small group of volunteers, and in 2006 a Peptides review placed the compound within the wider history of melanocortin drug design. Most research since has been preclinical. The full list, with models and designs, is in our cyclic analogue research studies library.

Melanotan II vial specifications

A white lyophilised solid, molecular weight about 1,024 g/mol, fills the base of each vial beneath a stopper and crimped cap. The printed label carries the compound, 10mg fill, lot reference and a freezer temperature. The lactam ring resists proteolysis, yet the indole of its tryptophan still reacts to light, so the carton belongs in frozen storage, minus 20 °C. Certificates of analysis are issued by lot reference.

Melanotan II price in Australia

The 10mg vial has one price in Australian dollars, so each milligram costs a tenth of it. Buying a whole receptor panel's requirement at once keeps the pan-agonist control on one lot from the first plate to the last.

Melanotan II 10mg: where to buy in Australia

Ten milligrams covers a full selectivity panel with room for repeats, since cell assays use it at very small concentrations. For a serial dilution series, 4 mL of water sets the cyclic peptide at 2.5 mg/mL; for a denser stock, 2 mL sets it at 5.

Melanotan II vial or nasal spray: which format to order

The lyophilised vial is the laboratory format, giving full control of diluent and concentration and a long frozen shelf life. A ready-made nasal spray version also appears as a separate listing, pre-mixed at one strength, and the starter kit pairs the vial with water and consumables. For receptor work, the vial remains the standard purchase.

Best place to buy Melanotan II in Australia

• A set-price 10mg vial
• Lot code with its own certificate
• Packed upright, crimp protected
• PT-141 and Melanotan 1 for comparison
• Australian stock, Australian dispatch

How to buy Melanotan II online

• Place the 10mg vial in the cart
• Add comparators your panel needs
• Include water for reconstitution
• Declare age and research use
• Log the lot on arrival

Melanotan II calculator: stock strength from 10mg

Stock strength is ten milligrams divided by the water volume:

• With 1 mL: 10 mg/mL
• With 2 mL: 5 mg/mL
• With 5 mL: 2 mg/mL
• With 10 mL: 1 mg/mL

Our calculator returns any other volume. Grab bacteriostatic water 10mL from lab supplies in the same order.

Is Melanotan II available in Australia

Only for laboratory research. The cyclic analogue is not an ARTG-listed good, has never received TGA approval, and the TGA has issued public warnings about melanotan products being sold for personal use. We supply it for in-vitro study alone. Scheduling is decided under the Poisons Standard; look up its present wording for your institution before you order.

Melanotan II for sale Australia wide

Our Australian team ships each order to universities and private laboratories across the country, including Newcastle, Geelong, Toowoomba and Bunbury. Melanotan 1, Kisspeptin-10 and other ligands from our melanocortin research range travel in the same box.

Questions about Melanotan II 10mg