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Buy Melanocortin Research Peptides and Melanotan Peptides in Australia
Receptor ligands for the melanocortin family, MC1R through MC5R: the linear analogue Melanotan 1, the non-selective cyclic Melanotan II and the MC4R and MC3R preferring PT-141, plus Kisspeptin-10 for KISS1R work. All are priced 10mg lyophilised vials with a printed lot number, dispatched from Australian stock for in-vitro receptor research.
Buy melanocortin research peptides in Australia: MC1R to MC5R ligands
The five melanocortin receptors, MC1R to MC5R, are class A G protein-coupled receptors that couple chiefly to Gs and cAMP. Their endogenous agonists (alpha-MSH, beta-MSH, gamma-MSH and ACTH) are all cleaved from pro-opiomelanocortin, and the family is unusual in also having endogenous antagonists, agouti signalling protein and agouti-related protein. MC2R responds to ACTH alone, so research ligands are judged by their selectivity across MC1R, MC3R, MC4R and MC5R.
Melanocortin peptides price list
| Product | Amount | Price |
|---|---|---|
| Melanotan 1 | 10 mg | $89.99 |
| Melanotan II | 10 mg | $89.99 |
| PT-141 | 10 mg | $109.99 |
| Kisspeptin-10 | 5 mg | Price to confirm |
| Kisspeptin-10 | 10 mg | $99.99 |
| Melanotan II nasal spray | 10 mg / 10 ml | $89.99 |
| PT-141 nasal spray | 10 mg / 10 ml | $109.99 |
Melanotan 1, Melanotan II and PT-141 are each priced as a single 10mg vial. Kisspeptin-10 is priced at 10mg, and its 5mg vial is quoted on request.
Melanotan peptides compared: buy by structure and selectivity
Melanotan 1 (afamelanotide) keeps the linear 13 residue alpha-MSH backbone but adds Nle4 and D-Phe7, raising stability and potency over the native hormone; MC1R is its main target. Melanotan II shortens the chain to seven residues closed by a lactam bridge and shows little discrimination among MC1R, MC3R, MC4R and MC5R, the reason it serves as the non-selective reference ligand. Both came out of the University of Arizona. The lactam bridge is what separates them: it constrains the His-Phe-Arg-Trp core that every melanocortin agonist shares, shortening the molecule while preserving receptor contact.
PT-141 and MC4R: buy melanocortin peptides for central receptor studies
PT-141, bremelanotide, was developed by Palatin Technologies and differs from Melanotan II only at the C-terminus, where a free carboxylic acid replaces the amide. Its preference runs to MC4R and MC3R, subtypes expressed centrally and examined in hypothalamic energy balance signalling. Running PT-141 against Melanotan II therefore isolates the effect of a single terminal modification on receptor preference.
Kisspeptin-10 in the melanocortin research peptides range to order
Kisspeptin-10 is the C-terminal decapeptide of kisspeptin, the KISS1 gene product, and the shortest fragment retaining full agonist activity at KISS1R, also called GPR54. It is not a melanocortin. It sits here because the same hypothalamic neuroendocrine laboratories order it, and because KISS1R couples through Gq, a useful contrast with the Gs-coupled melanocortin receptors in second messenger assays.
How researchers choose which melanocortin peptides to buy
Build the panel around selectivity. Melanotan 1 covers MC1R, PT-141 covers MC4R and MC3R, and Melanotan II provides the non-selective reference that confirms the assay responds at every subtype. Readouts are normally cAMP accumulation or reporter activity in cells expressing one receptor subtype. The alpha-MSH derived tripeptide KPV, used in inflammatory signalling, is listed under recovery research.
Our recommendation: best melanocortin peptides selectivity pack
We recommend ordering Melanotan II and PT-141 together as the first pair. Because the two differ at one terminal group, any shift in MC subtype response is attributable to that change, and both are priced 10mg vials that can be ordered without a quote. Add Melanotan 1 when MC1R needs its own arm.
Melanocortin peptides Australia: labels, delivery and supplies
Melanocortin vial labels carry compound, strength, lot code and storage. Each melanocortin lot has its own certificate of analysis, supplied when you cite that code. Australia is the dispatch point for all melanocortin peptides Australia wide. Reconstitute with BAC water for peptides from our lab supplies. Endocrine groups also draw on growth hormone research for pituitary axis compounds.
Storing melanocortin research peptides after you buy
Unopened Melanotan and PT-141 vials go in a dark -20 °C freezer, because the tryptophan residue in each sequence is vulnerable to photo-oxidation. Dissolved melanocortin solutions stay refrigerated, 2 to 8 °C, and are never refrozen. The cyclic structure of Melanotan II and PT-141 gives greater stability in solution than the linear Melanotan 1.
Melanocortin peptides Australia: research only and TGA scheduling
Melanotan 1, Melanotan II, PT-141 and Kisspeptin-10 are supplied solely as in-vitro receptor research materials. Registration as therapeutic goods does not apply to any of them, administering them to people or animals is outside their scope, and purchasers must be adults. The TGA controls melanocortin peptide scheduling through the Poisons Standard and revises entries, so confirm the current schedule for your institution before ordering.