Buy Mazdutide Peptide in Australia
Buy Mazdutide in Australia from Macropus Peptides as a 10mg research vial, quoted on request while a list price is set. Mazdutide is a lipidated peptide modelled on oxyntomodulin, a natural gut hormone, and it activates both the GLP-1 receptor and the glucagon receptor from one molecule, without the GIP receptor activity found in dual and triple incretin agonists. That receptor pair makes it a useful comparator in studies that separate the glucagon contribution from the incretin one. The vial holds lyophilised powder under a crimped seal, labelled with compound, strength, lot number and storage temperature, and a certificate of analysis is issued for every lot. Send an enquiry for the current price, add bacteriostatic water to the same order, and the parcel ships from local Australian stock to any Australian address. Mazdutide is supplied to adults aged 18 and over for in-vitro laboratory research only, not for human or veterinary use.
| Compound | Mazdutide |
|---|---|
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Metabolic research |
| Storage | -20 °C, protect from light |
| Testing | HPLC purity and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
Mazdutide 10mg vial
Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.
Buy Mazdutide Australia: 10mg Research Vial
Macropus Peptides lists this GLP-1 and glucagon receptor dual agonist as one 10mg vial of freeze-dried research peptide. Pricing is still being settled, so each order opens with a quote, and every vial is lot-released from a single managed source.
Mazdutide Australia: what is Mazdutide
Mazdutide, known in development as LY3305677 and later as IBI362, is a synthetic peptide built on the pattern of oxyntomodulin. Oxyntomodulin is a 37 amino acid fragment of proglucagon that intestinal L cells release together with GLP-1, and it weakly activates both the GLP-1 and glucagon receptors. Because natural oxyntomodulin disappears from circulation in minutes, the synthetic version carries substitutions that resist peptidases plus an albumin-binding fatty acid, stretching activity to around a week. It has completed phase 3 trials, which makes it one of the more mature glucagon-containing agonists available as research material.
Mazdutide peptide: GLP-1 and glucagon receptor action in research
The GLP-1 receptor sits on pancreatic beta cells and on neurons that regulate appetite, and it amplifies glucose-dependent insulin release. The glucagon receptor is concentrated in the liver, where it controls glucose output, amino acid turnover and the oxidation of fatty acids. A peptide that engages both at once lets researchers test what the hepatic glucagon arm adds on top of incretin signalling. Because this molecule has no GIP receptor activity, it fills a specific gap in comparator panels: set beside a GLP-1-only agonist, Tirzepatide for GIP plus GLP-1, and Retatrutide for all three, it isolates the glucagon contribution cleanly.
Mazdutide research: what the published studies show
The human record began with a phase 1b multiple ascending study in EClinicalMedicine in 2021, which measured safety, tolerability and pharmacokinetics in Chinese adults. A randomised phase 2 study followed in Nature Communications in 2023, then phase 3 results in NEJM in 2025 covering cardiometabolic markers and safety. All three were run in China, and the preclinical receptor data came from the discovery programme behind them. Designs and measurements are summarised in our Mazdutide research studies library.
Mazdutide vial specifications
| Specification | Detail |
|---|---|
| Compound | Mazdutide |
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Metabolic research |
| Storage | -20 °C, protect from light |
A white lyophilised plug fills the base of the vial beneath a crimped seal. Printing on the glass identifies the oxyntomodulin analogue, its 10mg content, a lot code and the freezer temperature. We pair that lot code with its certificate on request, and the unopened vial is kept at -20 °C with light excluded.
Mazdutide price in Australia
| Option | Price |
|---|---|
| Mazdutide 10mg | Price to confirm |
No list price is set for the 10mg vial yet, so it displays as price to confirm. Send an enquiry and we come back with the figure for whichever lot is in stock; divide it by ten for a per-milligram cost to set against other dual agonists.
Mazdutide 10mg: where to buy in Australia
Ten milligrams covers receptor activation assays, a comparator arm in an incretin panel, or method development on one lot. Groups running it head to head with Survodutide can reconstitute both 10mg vials the same way so pipetting volumes match across arms. Stock strengths for this vial:
- 2 mL added: 5 mg per mL
- 4 mL added: 2.5 mg per mL
Best place to buy Mazdutide Australia
- A GLP-1 and glucagon dual agonist with no GIP receptor activity
- Quotes returned for the lot currently held in Australia
- Lot code on the vial, matched to a batch certificate
- Domestic dispatch with no international customs step
- Dual, triple and amylin comparators in one order
Mazdutide how to get: buy Mazdutide online
- Select the 10mg vial and submit a quote request
- Accept the quote and set the vial count
- Name bacteriostatic water on the order if required
- Finish checkout as an adult research purchaser
- Keep the lot code and ask for the certificate
Mazdutide calculator: working out bac water volumes
Type a diluent volume into the calculator on the listing and it returns the resulting Mazdutide concentration, in milligram and microgram units. Handy figures:
- 1 mL: 10 mg per mL
- 2 mL: 5 mg per mL
- 5 mL: 2 mg per mL
Agitation can clump lipidated chains like this one, so let bacteriostatic water slide down the vial wall and turn it slowly between the fingers. More diluents are listed in lab supplies.
Is Mazdutide available in Australia
Only as a research peptide. The oxyntomodulin analogue is absent from the ARTG and unapproved by the TGA; supplying it for human or animal use is off limits, and our sales cover in-vitro benchwork only. Research peptides fall under the Poisons Standard, which the TGA amends periodically, so establish the current position for your organisation first.
Mazdutide for sale Australia wide
Vials leave our Australian facility for the capitals and for regional research sites, cushioned upright with the closure protected. It is most often ordered with Survodutide, the other GLP-1 and glucagon dual agonist we carry, and with Cagrilintide for amylin work. Browse the full metabolic research range.
References
- IBI362 (LY3305677), a weekly-dose GLP-1 and glucagon receptor dual agonist, in Chinese adults with overweight or obesity: a randomised, placebo-controlled, multiple ascending dose phase 1b study. EClinicalMedicine. 2021.
- A phase 2 randomised controlled trial of mazdutide in Chinese overweight adults or adults with obesity. Nature Communications. 2023.
- Once-weekly mazdutide in Chinese adults with obesity or overweight. New England Journal of Medicine. 2025.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.