Buy IGF-1 LR3 Peptide in Australia

Choose strength: 1 MG

0.1mgPrice to confirm1mg$139.99

Buy IGF-1 LR3 in Australia from Macropus Peptides in 0.1mg and 1mg research vials. IGF-1 LR3 is an 83 amino acid analogue of insulin-like growth factor 1 with an arginine at position 3 and a 13 amino acid extension at its start, changes that sharply reduce capture by IGF binding proteins while keeping activity at the IGF-1 receptor. That makes it far more active per microgram in culture than native IGF-1, and it is widely used in cell culture and receptor signalling work. The 1mg vial is priced and ready to order, and the 0.1mg vial is quoted on request. Each vial holds lyophilised protein, sealed and labelled with compound, amount, lot number and storage temperature, and the certificate of analysis for its lot is available on request. Add bacteriostatic water or dilute acetic acid and the order is dispatched from Australian stock to any Australian address. IGF-1 LR3 is sold to adults 18 and over for in-vitro research only, not for human or veterinary use.

Compound	IGF-1 LR3
Amount	1 mg
Form	Lyophilised powder
Category	Growth hormone research
Storage	-20 °C, protect from light
Testing	HPLC purity and mass spectrometry identity, every batch
Certificate of analysis	Available for every lot, matched to the lot number on the label

IGF-1 LR3 1mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Diluent added (mL)

Buy IGF-1 LR3 Australia: 0.1mg and 1mg Vials

Macropus Peptides stocks this IGF-1 analogue in much smaller fills than most of our peptides, because it is active at very low concentrations: a 0.1mg vial, equal to 100 micrograms, and a 1mg vial. Only the larger fill is on a checkout price right now; the 100 microgram fill, made identically, is priced by quote.

What is IGF-1 LR3

Insulin-like growth factor 1 (IGF-1) is a 70 amino acid protein, held in shape by three disulfide bridges, whose sequence was published in the Journal of Biological Chemistry in 1978. It is the main hormone through which growth hormone acts on tissues. The LR3 analogue is a longer version of 83 amino acids: the glutamic acid at position 3 is replaced with arginine, the R3 in the name, and a 13 amino acid extension is added to the front, the L for long. Unlike the short synthetic peptides in our range, it is produced recombinantly. It is a laboratory reagent and has never been a medicine.

IGF-1 LR3 Australia: how it works in research

Cells in culture release IGF binding proteins that grab native IGF-1 and keep much of it away from its receptor. The two changes in the analogue greatly reduce that binding while leaving the analogue able to activate the IGF-1 receptor, a tyrosine kinase that signals through the PI3K and Akt pathway and the MAPK pathway. More of each microgram therefore reaches the receptor and stays active for longer. Researchers use it to study IGF-1 receptor signalling, cell growth and survival in culture, and muscle and other cell models, and it is a common growth supplement in serum-free culture media.

IGF-1 LR3 research: what the studies show

The sequence of native IGF-1 was set out in 1978 in the Journal of Biological Chemistry. A 1989 paper in the Biochemical Journal showed that IGF binding proteins blocked the actions of IGF-1 but not of a truncated form lacking its first three amino acids, pointing to the start of the chain as the key to binding protein capture. The design behind the analogue was reported in 1992 in the Journal of Molecular Endocrinology, which compared fusion analogues to separate binding protein affinity from receptor binding. A 1995 study in the Journal of Endocrinology examined organ growth and circulating IGF and binding protein levels in guinea pigs given the analogue. Summaries are in our IGF-1 LR3 research studies library.

IGF-1 LR3 vial specifications

The analogue is supplied as a small lyophilised pellet in a stoppered, crimped vial; at 0.1mg the pellet can be hard to see. The label shows the compound, amount, lot and storage temperature. Its certificate of analysis follows by email once you give us that lot. Keep the sealed vial at -20 °C and protect it from light until use.

IGF-1 LR3 price in Australia

The 1mg vial is the priced size and holds ten times the protein of the 0.1mg vial. Unless a project truly needs only a hundred micrograms, the 1mg vial is expected to be the better value per microgram once the smaller size is quoted.

IGF-1 LR3 1mg: where to buy in Australia

Most orders are for the 1mg vial, which covers extended culture work or a full signalling study on one lot. Taken up in 1 mL it forms a 1 mg per mL stock (1,000 micrograms per millilitre); in 2 mL, a 500 micrograms per millilitre stock. Stocks at this strength are then diluted into media or assay buffer.

IGF-1 LR3 0.1mg for small experiments

The 100 microgram vial suits a one-off experiment or a short test in a new cell line. In 1 mL it gives 100 micrograms per millilitre.

Best place to buy IGF-1 LR3 in Australia

• The 1mg vial priced and ready to ship, the 0.1mg vial quoted
• Both fills made to one specification
• Lot on each label with a certificate of analysis per lot
• Bacteriostatic water and acetic acid diluent in the same range
• Sent from our Australian shelves, with no overseas import step

How to buy IGF-1 LR3 online

• Put the 1mg vial in the cart, or request pricing on the 0.1mg size
• Choose the number of vials
• Add a diluent: bacteriostatic water or dilute acetic acid
• Complete payment after the adult and research-use declarations
• Record the lot for certificate requests

IGF-1 LR3 calculator: bac water for 1mg and 0.1mg

Because the fills are small, work in micrograms. The 1mg vial holds 1,000 micrograms: in 1 mL that is 1,000 micrograms per millilitre, in 2 mL it is 500, and in 5 mL it is 200. The 0.1mg vial holds 100 micrograms: in 1 mL that is 100 micrograms per millilitre, and in 0.5 mL it is 200. Many laboratories dissolve IGF analogues in a dilute acid such as our acetic acid solution before diluting further; bacteriostatic water is the alternative.

Is IGF-1 LR3 available in Australia

It is available for laboratory research only, which is how we sell it. Absent from the ARTG, the analogue is barred from any human or veterinary sale. Insulin-like growth factors are dealt with in the TGA's Poisons Standard, and its latest version determines what your organisation may hold.

IGF-1 LR3 for sale Australia wide

From Australian stock we send it to cell culture and signalling laboratories across Australia. For work further up the growth hormone axis, the growth hormone research range includes CJC-1295 no DAC, Ipamorelin and the HGH Fragment 176-191.

Questions about IGF-1 LR3